Postnatal ontogeny of POMC gene expression in the rat pituitary: an analysis by in situ hybridization histochemistry

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ID: 270240
1989
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Abstract
Postnatal development of proopiomelanocortin gene expression in the rat pituitary was examined using in situ hybridization histochemistry. In adult rats, a very high density of hybridization signals was seen in the intermediate lobe of the pituitary, while only a moderate density occurred in the anterior lobe. No evidence of hybridization was detected in the posterior lobe. At birth, both the intermediate and anterior lobes had low to moderate frequencies of hybridization signals but a rapid rise to moderate density was noted by the 8th postnatal day. Radioactive labelling in the intermediate lobe continued to increase sharply with age to reach a plateau at postnatal day 28, while hybridization signals in the anterior lobe levelled off at postnatal day 8 with no subsequent rise in density.
Reference Key
tohyama1989developmentalpostnatal Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors Ya-Qi Wang,Makoto Sato,Yasuhiro Morita,Koichi Noguchi,Hiroshi Kiyama,Masaya Tohyama;Ya-Qi Wang;Makoto Sato;Yasuhiro Morita;Koichi Noguchi;Hiroshi Kiyama;Masaya Tohyama;
Journal Developmental Brain Research
Year 1989
DOI
10.1016/0165-3806(89)90107-7
URL
https://sciprofiles.com/publication/view/cc4aa22656c6a99a0a38433242e34b1c
Keywords
gene expression rat pituitary proopiomelanocortin in situ hybridization histochemistry postnatal ontogeny

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