A single domain of yeast poly(A)-binding protein is necessary and sufficient for RNA binding and cell viability
Clicks: 221
ID: 270147
1987
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Abstract
The poly(A)-binding protein (PAB) gene of Saccharomyces cerevisiae is essential for cell growth. A 66-amino acid polypeptide containing half of a repeated N-terminal domain can replace the entire protein in vivo. Neither an octapeptide sequence conserved among eucaryotic RNA-binding proteins nor the …
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ab1987moleculara
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| Authors | Sachs AB;Davis RW;Kornberg RD;; |
| Journal | molecular and cellular biology |
| Year | 1987 |
| DOI |
DOI not found
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| URL | |
| Keywords |
National Center for Biotechnology Information
NCBI
NLM
MEDLINE
pubmed abstract
nih
national institutes of health
national library of medicine
research support
u.s. gov't
P.H.S.
carrier proteins / genetics
osmolar concentration
structure-activity relationship
cell division
binding sites
carrier proteins / metabolism*
cell survival
dna mutational analysis
poly a / metabolism*
r w davis
pmid:3313012
pmc367964
doi:10.1128/mcb.7.9.3268-3276.1987
a b sachs
r d kornberg
poly(a)-binding proteins
saccharomyces cerevisiae / physiology*
|
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