MYELOFIBROSIS IN CHILDREN: Experience at a Single Tertiary Care Center in India

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ID: 269948
2010
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Abstract
The authors describe 10 cases of myelofibrosis diagnosed and managed at their center over 16 years. There were 2 and 8 cases, respectively, of primary and secondary myelofibrosis. All patients presented with fever, pallor, hepatosplenomegaly, and/or lymphadenopathy. Hodgkin's lymphoma (n = 4), neuroblastoma (n = 1), thrombasthenic thrombopathy (n = 1), and retroperitoneal-mass (n = 1) were causal in 7 patients, whereas the diagnosis could not be established in a sole case of secondary myelofibrosis. Patients were managed with chemotherapy and appropriate care. However, outcome was poor. The authors emphasize variable clinical-laboratory spectrum of myelofibrosis, highlight management concerns, and demonstrate that prognosis/outcome depends upon appropriate management of the underlying condition.
Reference Key
dawar2010pediatricmyelofibrosis Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors Laxman Singh Arya,Vasantha Thavraj,D. Chandra,Ketan Prasad Kulkarni,R. Kumar,R. Dawar;Laxman Singh Arya;Vasantha Thavraj;D. Chandra;Ketan Prasad Kulkarni;R. Kumar;R. Dawar;
Journal pediatric hematology and oncology
Year 2010
DOI
10.3109/08880011003739430
URL
https://sciprofiles.com/publication/view/12a0dd2f6b99e94da081a8dc5bfe1096
Keywords
Fever Children neuroblastoma hodgkin's lymphoma clinical laboratory single tertiary tertiary care secondary myelofibrosis

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