High frequency of resistant viruses harboring different mutations in amantadine-treated children with influenza

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ID: 269891
2003
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Ranked #89 of 444 articles by views in The Journal of infectious diseases

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Abstract
Clinical samples from 15 amantadine-treated children were collected serially-before, during, and/or after treatment-and were studied to determine the actual prevalence, timing, and clinical implications of M2 mutational events. After viral RNA extraction and reverse-transcriptase polymerase chain re …
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Authors Shiraishi K;Mitamura K;Sakai-Tagawa Y;Goto H;Sugaya N;Kawaoka Y;;
Journal The Journal of infectious diseases
Year 2003
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