A Novel Botulinum Neurotoxin, Previously Reported as Serotype H, Has a Hybrid-Like Structure With Regions of Similarity to the Structures of Serotypes A and F and Is Neutralized With Serotype A Antitoxin

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2016
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Abstract
Botulism is a potentially fatal paralytic disease caused by the action of botulinum neurotoxin (BoNT) on nerve cells. There are 7 known serotypes (A-G) of BoNT and up to 40 genetic variants. Clostridium botulinum strain IBCA10-7060 was recently reported to produce BoNT serotype B (BoNT/B) and a nove …
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Authors Maslanka SE;Lúquez C;Dykes JK;Tepp WH;Pier CL;Pellett S;Raphael BH;Kalb SR;Barr JR;Rao A;Johnson EA;;
Journal The Journal of infectious diseases
Year 2016
DOI
DOI not found
URL
http://www.ncbi.nlm.nih.gov/pubmed/26068781
Keywords
National Center for Biotechnology Information NCBI NLM MEDLINE Mice animals humans pubmed abstract nih national institutes of health national library of medicine research support u.s. gov't N.I.H. Extramural P.H.S. pmid:26068781 pmc4704661 doi:10.1093/infdis/jiv327 susan e maslanka carolina lúquez eric a johnson biological assay botulinum antitoxin / pharmacology* botulinum toxins / chemistry* botulinum toxins / classification*

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