Endosomal cAMP production broadly impacts the cellular phosphoproteome

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2021
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Abstract
Endosomal signaling downstream of G-protein-coupled receptors (GPCRs) has emerged as a novel paradigm with important pharmacological and physiological implications. However, our knowledge of the functional consequences of intracellular signaling is incomplete. To begin to address this gap, we combin …
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Authors Tsvetanova NG;Trester-Zedlitz M;Newton BW;Peng GE;Johnson JR;Jimenez-Morales D;Kurland AP;Krogan NJ;von Zastrow M;;
Journal The Journal of biological chemistry
Year 2021
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