A novel method for SNP detection using a new duplex-specific nuclease from crab hepatopancreas

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ID: 269716
2002
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Abstract
We have characterized a novel nuclease from the Kamchatka crab, designated duplex-specific nuclease (DSN). DSN displays a strong preference for cleaving double-stranded DNA and DNA in DNA-RNA hybrid duplexes, compared to single-stranded DNA. Moreover, the cleavage rate of short, perfectly matched DN …
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da2002genomea Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors Shagin DA;Rebrikov DV;Kozhemyako VB;Altshuler IM;Shcheglov AS;Zhulidov PA;Bogdanova EA;Staroverov DB;Rasskazov VA;Lukyanov S;;
Journal genome research
Year 2002
DOI
DOI not found
URL
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=12466298
Keywords
National Center for Biotechnology Information NCBI NLM MEDLINE genetic animals pubmed abstract nih national institutes of health national library of medicine models research support non-u.s. gov't Molecular Sequence Data Polymorphism endonucleases / genetics* cloning single nucleotide / genetics* liver / enzymology pmid:12466298 pmc187582 doi:10.1101/gr.547002 dmitry a shagin denis v rebrikov sergey lukyanov anomura / enzymology* anomura / genetics* molecular / methods nucleic acid heteroduplexes / genetics* oligonucleotides / chemical synthesis oligonucleotides / metabolism pancreas / enzymology substrate specificity / genetics

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