Disruption of the ARF–Mdm2–p53 tumor suppressor pathway in Myc-induced lymphomagenesis
Clicks: 158
ID: 269581
1999
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Abstract
Transgenic mice expressing the c-Myc oncogene driven by the immunoglobulin heavy chain enhancer (Eμ) develop B-cell lymphoma and exhibit a mean survival time of approximately 6 months. The protracted latent period before the onset of frank disease ...
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| Reference Key |
cleveland1999genesdisruption
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|---|---|
| Authors | Christine M. Eischen, Jason D. Weber, Martine F. Roussel, Charles J. Sherr, John L. Cleveland;Christine M. Eischen;Jason D. Weber;Martine F. Roussel;Charles J. Sherr;John L. Cleveland; |
| Journal | genes & development |
| Year | 1999 |
| DOI |
10.1101/gad.13.20.2658
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| URL | |
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