C11orf95-RELA fusion drives aberrant gene expression through the unique epigenetic regulation for ependymoma formation

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ID: 269571
2021
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Abstract
Recurrent C11orf95-RELA fusions (RELA[FUS] ) are the hallmark of supratentorial ependymomas. The presence of RELA as the fusion partner indicates a close association of aberrant NF-κB activity with tumorigenesis. However, the oncogenic role of ...
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ichimura2021actac11orf95-rela Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors Tatsuya Ozawa, Syuzo Kaneko, Frank Szulzewsky, Zhiwei Qiao, Mutsumi Takadera, Yoshitaka Narita, Tadashi Kondo, Eric C. Holland, Ryuji Hamamoto, Koichi Ichimura;Tatsuya Ozawa;Syuzo Kaneko;Frank Szulzewsky;Zhiwei Qiao;Mutsumi Takadera;Yoshitaka Narita;Tadashi Kondo;Eric C. Holland;Ryuji Hamamoto;Koichi Ichimura;
Journal acta neuropathologica communications
Year 2021
DOI
10.1186/s40478-021-01135-4
URL
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7941712/?report=classic
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