A randomized, double-blind, placebo-controlled trial of CDP571, a humanized monoclonal antibody to tumour necrosis factor-alpha, in patients with corticosteroid-dependent Crohn's disease

Clicks: 315
ID: 269350
2005
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Abstract
The CDP571 was effective for corticosteroid-sparing at week 16 but not week 10, and was well-tolerated in patients with corticosteroid-dependent Crohn's disease.
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Authors Feagan BG;Sandborn WJ;Baker JP;Cominelli F;Sutherland LR;Elson CO;Salzberg BA;Archambault A;Bernstein CN;Lichtenstein GR;Heath PK;Cameron S;Hanauer SB;;
Journal alimentary pharmacology & therapeutics
Year 2005
DOI
DOI not found
URL
https://www.pubmed.gov/15709987/
Keywords
National Center for Biotechnology Information NCBI NLM MEDLINE humans pubmed abstract nih national institutes of health national library of medicine treatment outcome research support non-u.s. gov't adult female male middle aged Drug Administration Schedule Clinical Trial Randomized Controlled Trial Antibodies Monoclonal / therapeutic use* Double-Blind Method severity of illness index Gastrointestinal Agents / therapeutic use* monoclonal / adverse effects crohn disease / drug therapy* anti-inflammatory agents non-steroidal / therapeutic use* phase ii anti-inflammatory agents / adverse effects quality of life tumor necrosis factor-alpha / antagonists & inhibitors anti-inflammatory agents / administration & dosage prednisolone / administration & dosage crohn disease / pathology pmid:15709987 doi:10.1111/j.1365-2036.2005.02336.x b g feagan w j sandborn s b hanauer budesonide / administration & dosage

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