Pds5 is required for homologue pairing and inhibits synapsis of sister chromatids during yeast meiosis

Clicks: 118
ID: 269203
2009
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Abstract
During meiosis, homologues become juxtaposed and synapsed along their entire length. Mutations in the cohesin complex disrupt not only sister chromatid cohesion but also homologue pairing and synaptonemal complex formation. In this study, we report that ...
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Authors Hui Jin, Vincent Guacci, Hong-Guo Yu;Hui Jin;Vincent Guacci;Hong-Guo Yu;
Journal the journal of cell biology
Year 2009
DOI
10.1083/jcb.200810107
URL
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2742186/
Keywords
National Center for Biotechnology Information NCBI NLM MEDLINE genetic pubmed abstract nih national institutes of health national library of medicine research support non-u.s. gov't recombination recombinant fusion proteins / genetics chromosomes cell cycle proteins / genetics cell cycle proteins / metabolism* recombinant fusion proteins / metabolism chromosomal proteins dna topoisomerases vincent guacci non-histone / metabolism fungal / metabolism dna repair meiosis / physiology* saccharomyces cerevisiae* / genetics type ii / genetics type ii / metabolism saccharomyces cerevisiae proteins / genetics saccharomyces cerevisiae proteins / metabolism* non-histone / genetics fungal / ultrastructure chromosome segregation pmid:19736318 pmc2742186 doi:10.1083/jcb.200810107 hui jin hong-guo yu chromatids / metabolism* chromosome pairing* dna breaks double-stranded endodeoxyribonucleases rad51 recombinase / genetics rad51 recombinase / metabolism saccharomyces cerevisiae* / metabolism ubiquitin-protein ligases / genetics ubiquitin-protein ligases / metabolism

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