SREBP-2, a second basic-helix-loop-helix-leucine zipper protein that stimulates transcription by binding to a sterol regulatory element

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ID: 269026
1993
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Ranked #12 of 292 articles by views in Proceedings of the National Academy of Sciences of the United States of America

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Abstract
We report the cDNA cloning of SREBP-2, the second member of a family of basic-helix-loop-helix-leucine zipper (bHLH-Zip) transcription factors that recognize sterol regulatory element 1 (SRE-1). SRE-1, a conditional enhancer in the promoters for the low density lipoprotein receptor and 3-hydroxy-3-m …
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x1993proceedingssrebp-2, Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors Hua X;Yokoyama C;Wu J;Briggs MR;Brown MS;Goldstein JL;Wang X;;
Journal Proceedings of the National Academy of Sciences of the United States of America
Year 1993
DOI
DOI not found
URL
http://www.ncbi.nlm.nih.gov/pubmed/7903453
Keywords
National Center for Biotechnology Information NCBI NLM MEDLINE genetic humans pubmed abstract nih national institutes of health national library of medicine research support non-u.s. gov't u.s. gov't amino acid sequence conserved sequence Comparative Study P.H.S. cell line x wang enhancer elements genetic* DNA-Binding Proteins / metabolism* Nuclear Proteins / metabolism* Receptors Transcription Factors / metabolism* Molecular Sequence Data Promoter Regions transcription sequence homology amino acid kinetics transfection transcription factors / chemistry* gene expression* binding sites mutagenesis sterol regulatory element binding protein 1 point mutation chloramphenicol o-acetyltransferase / biosynthesis leucine zippers* ldl / genetics* sterols / pharmacology* nuclear proteins / chemistry c yokoyama ccaat-enhancer-binding proteins* helix-loop-helix motifs* site-directed pmid:7903453 pmc48032 doi:10.1073/pnas.90.24.11603 x hua dna-binding proteins / chemistry* hydroxymethylglutaryl-coa synthase / biosynthesis hydroxymethylglutaryl-coa synthase / genetics* ldl / biosynthesis sterol regulatory element binding protein 2

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