Tumor resistance to ferroptosis driven by Stearoyl-CoA Desaturase-1 (SCD1) in cancer cells and Fatty Acid Biding Protein-4 (FABP4) in tumor microenvironment promote tumor recurrence

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ID: 268930
2021
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Abstract
This finding unveils that it is worth taking advantage of tumor lipid addiction, as a tumor vulnerability to design novel treatment strategy to prevent cancer recurrence.
Reference Key
g2021redoxtumor Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors Luis G, Godfroid A, Nishiumi S, Cimino J, Blacher S, Maquoi E, Wery C, Collignon A, Longuespée R, Montero-Ruiz L, Dassoul I, Maloujahmoum N, Pottier C, Mazzucchelli G, Depauw E, Bellahcène A, Yoshida M, Noel A, Sounni NE
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Journal Redox biology
Year 2021
DOI
DOI not found
URL
http://www.ncbi.nlm.nih.gov/pubmed/34030117
Keywords
National Center for Biotechnology Information NCBI NLM MEDLINE local tumor microenvironment humans pubmed abstract nih national institutes of health national library of medicine research support non-u.s. gov't Fatty Acids neoplasm recurrence fatty acid-binding proteins pmid:34030117 pmc8163990 doi:10.1016/j.redox.2021.102006 géraldine luis adrien godfroid nor eddine sounni endothelial cells / metabolism ferroptosis* stearoyl-coa desaturase / metabolism

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