The in vivo response of stem and other undifferentiated spermatogonia to the reversible inhibition of glial cell line-derived neurotrophic factor signaling in the adult

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ID: 268850
2012
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Abstract
Maintaining adequate numbers of spermatogonial stem cells is required for the production of the millions of sperm required for male fertility. To date, however, the mechanisms that regulate the size of this pool in the adult are poorly defined. Glial cell line-derived neurotrophic factor (GDNF) is r …
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j2012stemthe Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors Savitt J;Singh D;Zhang C;Chen LC;Folmer J;Shokat KM;Wright WW;;
Journal stem cells (dayton, ohio)
Year 2012
DOI
DOI not found
URL
https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=22232066&dopt=Abstract
Keywords
National Center for Biotechnology Information NCBI NLM MEDLINE Mice animals pubmed abstract nih national institutes of health national library of medicine research support male N.I.H. Extramural signal transduction* stem cells / metabolism* aging / physiology* biomarkers / metabolism stem cells / cytology* testis / metabolism testis / cytology pmid:22232066 pmc3894909 doi:10.1002/stem.1028 joseph savitt dolly singh william w wright amino acid substitution / genetics cell differentiation* glial cell line-derived neurotrophic factor / metabolism* proto-oncogene proteins c-ret / metabolism spermatogonia / cytology* spermatogonia / metabolism

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