Gene expression and cell cycle arrest mediated by transcription factor DMP1 is antagonized by D-type cyclins through a cyclin-dependent-kinase-independent mechanism

Clicks: 298
ID: 268848
1998
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Abstract
A novel 761-amino-acid transcription factor, DMP1, contains a central DNA binding domain that includes three imperfect myb repeats flanked by acidic transactivating domains at the amino and carboxyl termini. D-type cyclins associate with a region of the DMP1 DNA binding domain immediately adjacent t …
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Authors Inoue K;Sherr CJ;;
Journal molecular and cellular biology
Year 1998
DOI
DOI not found
URL
http://www.ncbi.nlm.nih.gov/pubmed/9488476
Keywords
National Center for Biotechnology Information NCBI NLM MEDLINE Mice gene expression animals humans pubmed abstract nih national institutes of health national library of medicine research support non-u.s. gov't u.s. gov't P.H.S. cell line 3T3 Cells Transcription Factors / metabolism* chromosome mapping recombinant fusion proteins / genetics transcription factors / genetics dna / metabolism transcriptional activation cell division binding sites recombinant fusion proteins / metabolism cell cycle* cyclin-dependent kinases / genetics cyclin-dependent kinases / metabolism* k inoue c j sherr pmid:9488476 pmc108874 doi:10.1128/mcb.18.3.1590 cyclin d1 / genetics cyclin d1 / metabolism* cyclin-dependent kinase 4 proto-oncogene proteins* spodoptera / cytology transcription factors / antagonists & inhibitors

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