Mismatch repair genes on chromosomes 2p and 3p account for a major share of hereditary nonpolyposis colorectal cancer families evaluable by linkage

Clicks: 413
ID: 268767
1994
Free PDF
Article Quality & Performance Metrics
Overall Quality
Not rated
Combines reader engagement with the AI quality analysis. This article has not been analysed, so there is no overall score — reader engagement is measured and shown alongside.
AI Quality Assessment
Not analyzed
Readership in this journal
Popular

Ranked #2 of 51 articles by views in American journal of human genetics

Most read Least read

Bar heights use a square-root scale.

Mint this article as an NFT
Not yet minted

Create a permanent, verifiable on-chain record of this article on the Scimatic Network. The NFT is held in your Journament account, and you can withdraw it to your own wallet at any time.

5 SUSD one-off · no wallet required
Sign in to mint
Abstract
Two susceptibility loci for hereditary nonpolyposis colorectal cancer (HNPCC) have been identified, and each contains a mismatch repair gene: MSH2 on chromosome 2p and MLH1 on chromosome 3p. We studied the involvement of these loci in 13 large HNPCC kindreds originating from three different continen …
Reference Key
m1994americanmismatch Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors Nyström-Lahti M;Parsons R;Sistonen P;Pylkkänen L;Aaltonen LA;Leach FS;Hamilton SR;Watson P;Bronson E;Fusaro R;;
Journal American journal of human genetics
Year 1994
DOI
DOI not found
URL
https://www.ncbi.nlm.nih.gov/pubmed/7942843
Keywords
National Center for Biotechnology Information NCBI NLM MEDLINE humans pubmed abstract nih national institutes of health national library of medicine research support non-u.s. gov't u.s. gov't adult female male middle aged P.H.S. DNA human Genetic Markers mutation chromosome mapping chromosomes pedigree genetic linkage pmid:7942843 pmc1918295 m nyström-lahti r parsons r fusaro pair 2* pair 3* colorectal neoplasms hereditary nonpolyposis / blood hereditary nonpolyposis / genetics* dna repair / genetics* satellite / blood satellite / isolation & purification lod score MSH2 linkage families repair mismatch mlh1 locus kindreds

Citations

No citations found. To add a citation, contact the admin at info@scimatic.org

Comments

No comments yet. Be the first to comment on this article.