Single-molecule sequencing of an individual human genome
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ID: 268757
2009
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Abstract
Recent advances in high-throughput DNA sequencing technologies have enabled order-of-magnitude improvements in both cost and throughput. Here we report the use of single-molecule methods to sequence an individual human genome. We aligned billions of 24- to 70-bp reads (32 bp average) to approximatel …
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d2009naturesingle-molecule
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| Authors | Pushkarev D;Neff NF;Quake SR;; |
| Journal | Nature Biotechnology |
| Year | 2009 |
| DOI |
DOI not found
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| URL | |
| Keywords |
National Center for Biotechnology Information
NCBI
NLM
MEDLINE
humans
pubmed abstract
nih
national institutes of health
national library of medicine
reproducibility of results
research support
u.s. gov't
non-p.h.s.
N.I.H.
Extramural
Sequence Analysis
genome
genomics / methods*
Polymorphism
DNA / methods*
computer simulation
single nucleotide
human*
pmid:19668243
pmc4117198
doi:10.1038/nbt.1561
dmitry pushkarev
norma f neff
stephen r quake
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