Single-molecule sequencing of an individual human genome

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ID: 268757
2009
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Abstract
Recent advances in high-throughput DNA sequencing technologies have enabled order-of-magnitude improvements in both cost and throughput. Here we report the use of single-molecule methods to sequence an individual human genome. We aligned billions of 24- to 70-bp reads (32 bp average) to approximatel …
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d2009naturesingle-molecule Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors Pushkarev D;Neff NF;Quake SR;;
Journal Nature Biotechnology
Year 2009
DOI
DOI not found
URL
http://www.ncbi.nlm.nih.gov/pubmed/19668243
Keywords
National Center for Biotechnology Information NCBI NLM MEDLINE humans pubmed abstract nih national institutes of health national library of medicine reproducibility of results research support u.s. gov't non-p.h.s. N.I.H. Extramural Sequence Analysis genome genomics / methods* Polymorphism DNA / methods* computer simulation single nucleotide human* pmid:19668243 pmc4117198 doi:10.1038/nbt.1561 dmitry pushkarev norma f neff stephen r quake

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