The c-myc oncogene driven by immunoglobulin enhancers induces lymphoid malignancy in transgenic mice

Clicks: 481
ID: 268545
1970
Free PDF
Article Quality & Performance Metrics
Overall Quality
Not rated
Combines reader engagement with the AI quality analysis. This article has not been analysed, so there is no overall score — reader engagement is measured and shown alongside.
AI Quality Assessment
Not analyzed
Readership in this journal
Popular

Ranked #20 of 375 articles by views in Nature

Most read Least read

Bar heights use a square-root scale. Only the 120 most-read articles are drawn; the journal has 375 in total.

Mint this article as an NFT
Not yet minted

Create a permanent, verifiable on-chain record of this article on the Scimatic Network. The NFT is held in your Journament account, and you can withdraw it to your own wallet at any time.

5 SUSD one-off · no wallet required
Sign in to mint
Abstract
Transgenic mice bearing the cellular myc oncogene coupled to the immunoglobulin mu or kappa enhancer frequently develop a fatal lymphoma within a few months of birth. Since the tumours represent represent both immature and mature B lymphocytes, constitutive c-myc expression appears to be highly leuk …
Reference Key
jm1970naturethe Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors Adams JM;Harris AW;Pinkert CA;Corcoran LM;Alexander WS;Cory S;Palmiter RD;Brinster RL;;
Journal Nature
Year 1970
DOI
DOI not found
URL
http://www.ncbi.nlm.nih.gov/pubmed/3906410
Keywords
National Center for Biotechnology Information NCBI NLM MEDLINE genetic Mice gene expression regulation animals pubmed abstract nih national institutes of health national library of medicine research support non-u.s. gov't u.s. gov't P.H.S. DNA Genes enhancer elements genetic* recombination transcription cell differentiation proto-oncogene proteins / genetics* recombinant oncogenes* pmid:3906410 doi:10.1038/318533a0 j m adams a w harris r l brinster b-lymphocytes / pathology regulator* immunoglobulins / genetics* lymphoma / genetics*

Citations

No citations found. To add a citation, contact the admin at info@scimatic.org

Comments

No comments yet. Be the first to comment on this article.