A Role for the Cytoplasmic Polyadenylation Element in NMDA Receptor-Regulated mRNA Translation in Neurons

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ID: 268528
2001
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Abstract
The ability of neurons to modify synaptic connections based on activity is essential for information processing and storage in the brain. The induction of long-lasting changes in synaptic strength requires new protein synthesis and is often mediated by ...
Reference Key
fallon2001thea Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors David G. Wells, Xin Dong, Elizabeth M. Quinlan, Yi-Shuian Huang, Mark F. Bear, Joel D. Richter, Justin R. Fallon;David G. Wells;Xin Dong;Elizabeth M. Quinlan;Yi-Shuian Huang;Mark F. Bear;Joel D. Richter;Justin R. Fallon;
Journal The Journal of Neuroscience
Year 2001
DOI
10.1523/JNEUROSCI.21-24-09541.2001
URL
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6763028/
Keywords
National Center for Biotechnology Information NCBI NLM MEDLINE RNA animals pubmed abstract nih national institutes of health national library of medicine research support non-u.s. gov't u.s. gov't Neuronal Plasticity / physiology P.H.S. Cells Cultured Rats Receptors Messenger / genetics green fluorescent proteins luminescent proteins / genetics neurons / drug effects regulatory sequences transfection neurons / metabolism* messenger / metabolism* glutamic acid / pharmacology gene expression regulation / physiology synapses / physiology visual cortex / cytology pmid:11739565 pmc6763028 doi:10.1523/jneurosci.21-24-09541.2001 d g wells x dong j r fallon 3' untranslated regions / genetics 3' untranslated regions / metabolism calcium-calmodulin-dependent protein kinase type 2 calcium-calmodulin-dependent protein kinases / genetics calcium-calmodulin-dependent protein kinases / metabolism darkness excitatory amino acid agonists / pharmacology luminescent proteins / biosynthesis neurons / cytology photic stimulation / methods polyadenylation / drug effects protein biosynthesis / physiology* long-evans n-methyl-d-aspartate / agonists n-methyl-d-aspartate / antagonists & inhibitors n-methyl-d-aspartate / metabolism* nucleic acid / physiology* sensory deprivation / physiology visual cortex / metabolism

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