MG53 nucleates assembly of cell membrane repair machinery - Nature Cell Biology
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ID: 268469
2008
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Abstract
A phosphatidylserine-binding protein, MG53, is shown to participate in membrane repair. MG53 recruits vesicles to the repair site in an oxidation dependent manner and MG53-null mice develop progressive myopathy associated with defective membrane repair.
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| Authors | Chuanxi Cai;Haruko Masumiya;Noah Weisleder;Noriyuki Matsuda;Miyuki Nishi;Moonsun Hwang;Jae-Kyun Ko;Peihui Lin;Angela Thornton;Xiaoli Zhao;Zui Pan;Shinji Komazaki;Marco Brotto;Hiroshi Takeshima;Jianjie Ma;Chuanxi Cai;Haruko Masumiya;Noah Weisleder;Noriyuki Matsuda;Miyuki Nishi;Moonsun Hwang;Jae-Kyun Ko;Peihui Lin;Angela Thornton;Xiaoli Zhao;Zui Pan;Shinji Komazaki;Marco Brotto;Hiroshi Takeshima;Jianjie Ma; |
| Journal | Nature Cell Biology |
| Year | 2008 |
| DOI |
doi:10.1038/ncb1812
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