MG53 nucleates assembly of cell membrane repair machinery - Nature Cell Biology

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2008
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Abstract
A phosphatidylserine-binding protein, MG53, is shown to participate in membrane repair. MG53 recruits vesicles to the repair site in an oxidation dependent manner and MG53-null mice develop progressive myopathy associated with defective membrane repair.
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Authors Chuanxi Cai;Haruko Masumiya;Noah Weisleder;Noriyuki Matsuda;Miyuki Nishi;Moonsun Hwang;Jae-Kyun Ko;Peihui Lin;Angela Thornton;Xiaoli Zhao;Zui Pan;Shinji Komazaki;Marco Brotto;Hiroshi Takeshima;Jianjie Ma;Chuanxi Cai;Haruko Masumiya;Noah Weisleder;Noriyuki Matsuda;Miyuki Nishi;Moonsun Hwang;Jae-Kyun Ko;Peihui Lin;Angela Thornton;Xiaoli Zhao;Zui Pan;Shinji Komazaki;Marco Brotto;Hiroshi Takeshima;Jianjie Ma;
Journal Nature Cell Biology
Year 2008
DOI
doi:10.1038/ncb1812
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