Loss of Drosophila Ataxin-7, a SAGA subunit, reduces H2B ubiquitination and leads to neural and retinal degeneration
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ID: 268404
2014
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Abstract
The Spt–Ada–Gcn5–acetyltransferase (SAGA) chromatin-modifying complex possesses acetyltransferase and deubiquitinase activities. Within this modular complex, Ataxin-7 anchors the deubiquitinase activity to the larger complex. Here ...
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| Reference Key |
abmayr2014genesloss
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|---|---|
| Authors | Ryan D. Mohan, George Dialynas, Vikki M. Weake, Jianqi Liu, Skylar Martin-Brown, Laurence Florens, Michael P. Washburn, Jerry L. Workman, Susan M. Abmayr;Ryan D. Mohan;George Dialynas;Vikki M. Weake;Jianqi Liu;Skylar Martin-Brown;Laurence Florens;Michael P. Washburn;Jerry L. Workman;Susan M. Abmayr; |
| Journal | genes & development |
| Year | 2014 |
| DOI |
10.1101/gad.225151.113
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| URL | |
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