Blunted fasting-induced hypothalamic activation and refeeding hyperphagia in late-onset obesity

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ID: 268384
2009
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Abstract
Hormonal and metabolic factors signal the status of energy balance to hypothalamic nuclei. Obesity is characterized by neuronal, metabolic and hormonal alterations. We therefore hypothesized that hypothalamic responses to challenges of energy balance may differ between lean and obese animals. To tes …
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Authors Becskei C;Lutz TA;Riediger T;;
Journal neuroendocrinology
Year 2009
DOI
DOI not found
URL
http://www.ncbi.nlm.nih.gov/pubmed/19844081
Keywords
National Center for Biotechnology Information NCBI NLM MEDLINE Mice Inbred C57BL animals pubmed abstract nih national institutes of health national library of medicine research support non-u.s. gov't male transgenic age of onset green fluorescent proteins / genetics hyperinsulinism / physiopathology obesity / physiopathology* neurons / physiology intracellular signaling peptides and proteins / metabolism blood glucose / physiology pmid:19844081 doi:10.1159/000251723 csilla becskei thomas a lutz thomas riediger arcuate nucleus of hypothalamus / physiopathology* fasting / physiology* hyperphagia / physiopathology* hypothalamic area lateral / physiopathology* leptin / blood melanins / metabolism neuropeptide y / metabolism neuropeptides / metabolism orexins paraventricular hypothalamic nucleus / physiopathology* proto-oncogene proteins c-fos / metabolism

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