Distinct roles of BRCA2 in replication fork protection in response to hydroxyurea and DNA interstrand cross-links

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2020
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Abstract
DNA interstrand cross-links (ICLs) are a form of DNA damage that requires the interplay of a number of repair proteins including those of the Fanconi anemia (FA) and the homologous recombination (HR) pathways. Pathogenic variants in the essential gene ...
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Authors Kimberly A. Rickman, Raymond J. Noonan, Francis P. Lach, Sunandini Sridhar, Anderson T. Wang, Avinash Abhyankar, Athena Huang, Michael Kelly, Arleen D. Auerbach, Agata Smogorzewska;Kimberly A. Rickman;Raymond J. Noonan;Francis P. Lach;Sunandini Sridhar;Anderson T. Wang;Avinash Abhyankar;Athena Huang;Michael Kelly;Arleen D. Auerbach;Agata Smogorzewska;
Journal genes & development
Year 2020
DOI
10.1101/gad.336446.120
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