Bilateral Effect of the Unilateral Corneal Nerve Cut on Both Ocular Surface and Lacrimal Gland

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ID: 268158
2019
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Abstract
The unilateral corneal nerve severing resulted in activation of the immune cells on the ocular surface and dysregulated lacrimal secretion bilaterally through the bidirectional neuronal signals. It suggests that the unilateral corneal nerve damage may alter immune homeostasis and mechanistically par …
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Authors Lee HK;Kim KW;Ryu JS;Jeong HJ;Lee SM;Kim MK;;
Journal investigative ophthalmology & visual science
Year 2019
DOI
DOI not found
URL
https://www.pubmed.gov/30703211/
Keywords
National Center for Biotechnology Information NCBI NLM MEDLINE Mice animals pubmed abstract nih national institutes of health national library of medicine research support non-u.s. gov't female Inbred BALB C tears / physiology enzyme-linked immunosorbent assay t-lymphocytes flow cytometry dendritic cells / metabolism conjunctiva / metabolism mee kum kim lymph nodes / metabolism pmid:30703211 doi:10.1167/iovs.18-26051 hyo kyung lee kyoung woo kim cd4-positive t-lymphocytes / physiology cd8-positive t-lymphocytes / physiology coloring agents / metabolism cornea / innervation* cornea / metabolism cranial nerve diseases / etiology* cranial nerve diseases / immunology dry eye syndromes / etiology* dry eye syndromes / immunology lacrimal apparatus / innervation* lissamine green dyes / metabolism ophthalmic nerve / injuries* regulatory / physiology

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