Comprehensive Molecular Profiles of Functionally Effective MSC-Derived Extracellular Vesicles in Immunomodulation

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ID: 268101
2020
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Abstract
Accumulating evidence indicates that mesenchymal stem/stromal cell-derived extracellular vesicles (MSC-EVs) exhibit immunomodulatory effects by delivering therapeutic RNAs and proteins; however, the molecular mechanism underlying the EV-mediated immunomodulation is not fully understood. In this stud …
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Authors Kim H;Lee MJ;Bae EH;Ryu JS;Kaur G;Kim HJ;Kim JY;Barreda H;Jung SY;Choi JM;Shigemoto-Kuroda T;Oh JY;Lee RH;;
Journal molecular therapy : the journal of the american society of gene therapy
Year 2020
DOI
DOI not found
URL
https://www.pubmed.gov/32380062/
Keywords
National Center for Biotechnology Information NCBI NLM MEDLINE Mice animals humans pubmed abstract nih national institutes of health national library of medicine research support non-u.s. gov't N.I.H. Extramural Disease Models Animal Cells Cultured cell differentiation gene expression profiling transforming growth factor beta1 / metabolism proteomics cell proliferation c-reactive protein / metabolism cell culture techniques micrornas / genetics* pmid:32380062 pmc7335740 doi:10.1016/j.ymthe.2020.04.020 hyemee kim min joung lee ryang hwa lee c-reactive protein / genetics* extracellular vesicles / genetics extracellular vesicles / metabolism extracellular vesicles / transplantation* mesenchymal stem cells / cytology* mesenchymal stem cells / metabolism serial passage serum amyloid p-component / genetics* serum amyloid p-component / metabolism sjogren-larsson syndrome / genetics sjogren-larsson syndrome / metabolism sjogren-larsson syndrome / therapy* transforming growth factor beta1 / genetics*

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