17β-estradiol inhibits hepatic iNOS via the activation of the estrogen receptor ER-α and inhibition of erk1/2-mir-221 axis

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ID: 268053
1970
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Abstract
17β-Estradiol (E2) is known to negatively regulate inducible nitric oxide (NO) synthase (iNOS) expression via estrogen receptor alpha (ER-α) activation in aortic vascular smooth muscle cells.Therefore, we sought to determine whether E2 can inhibit iNOS in vivo in hepatic tissue via the activa …
Reference Key
a1970journal17β-estradiol Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors Panic A;Stanimirovic J;Obradovic M;Zafirovic S;Sudar-Milovanovic E;Petrovic N;Isenovic ER;;
Journal journal of biological regulators and homeostatic agents
Year 1970
DOI
DOI not found
URL
https://www.ncbi.nlm.nih.gov/pubmed/30574741
Keywords
National Center for Biotechnology Information NCBI NLM MEDLINE animals pubmed abstract nih national institutes of health national library of medicine male Rats liver / drug effects wistar micrornas / genetics* estradiol / pharmacology* pmid:30574741 a panic j stanimirovic e r isenovic estrogen receptor alpha / metabolism* liver / enzymology* map kinase signaling system* nitric oxide synthase type ii / metabolism*

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