Class IA Phosphatidylinositol 3-Kinase Inhibition Inhibits Cell Growth and Proliferation in Mantle Cell Lymphoma

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ID: 267927
2014
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Abstract
Constitutive activation of the phosphatidylinositol 3-kinase (PI3K)/Akt/mammalian target of rapamycin signaling pathway preferentially occurs in aggressive blastoid variants of mantle cell lymphoma (MCL) and is implicated in the pathogenesis of this disease. ...
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Authors Yoko Tabe, Linhua Jin, Marina Konopleva, Masato Shikami, Shinya Kimura, Michael Andreeff, Mark Raffeld, Takashi Miida;Yoko Tabe;Linhua Jin;Marina Konopleva;Masato Shikami;Shinya Kimura;Michael Andreeff;Mark Raffeld;Takashi Miida;
Journal acta haematologica
Year 2014
DOI
10.1159/000353164
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