Development of several organs that require inductive epithelial-mesenchymal interactions is impaired in LEF-1-deficient mice

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ID: 267668
1994
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Abstract
Lymphoid enhancer factor 1 (LEF-1) is a sequence-specific DNA-binding protein that is expressed in pre-B and T lymphocytes of adult mice, and in the neural crest, mesencephalon, tooth germs, whisker follicles, and other sites during embryogenesis. We have generated mice carrying a homozygous germ-li …
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Authors van Genderen C;Okamura RM;Fariñas I;Quo RG;Parslow TG;Bruhn L;Grosschedl R;;
Journal genes & development
Year 1994
DOI
DOI not found
URL
http://www.ncbi.nlm.nih.gov/pubmed/7958926
Keywords
National Center for Biotechnology Information NCBI NLM MEDLINE Mice animals pubmed abstract nih national institutes of health national library of medicine research support non-u.s. gov't u.s. gov't non-p.h.s. Genes dna-binding proteins / genetics transcription factors / genetics mammary glands Embryonic and Fetal Development* mutant strains pmid:7958926 doi:10.1101/gad.8.22.2691 c van genderen r m okamura r grosschedl dna-binding proteins / analysis* embryonic induction epithelium / embryology* lethal germ-line mutation hair / embryology lymphoid enhancer-binding factor 1 animal / embryology mesoderm / physiology* neural crest / embryology tooth / embryology transcription factors / analysis* trigeminal nerve / embryology

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