Virus induction of human IFN beta gene expression requires the assembly of an enhanceosome

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ID: 267488
1995
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Abstract
We present evidence that transcriptional activation of the human interferon-beta (IFN beta) gene requires the assembly of a higher order transcription enhancer complex (enhanceosome). This multicomponent complex includes at least three distinct transcription factors and the high mobility group prote …
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Authors Thanos D;Maniatis T;;
Journal Cell
Year 1995
DOI
DOI not found
URL
http://www.ncbi.nlm.nih.gov/pubmed/8548797
Keywords
National Center for Biotechnology Information NCBI NLM MEDLINE Drosophila gene expression regulation animals humans pubmed abstract nih national institutes of health national library of medicine research support non-u.s. gov't u.s. gov't P.H.S. enhancer elements sensitivity and specificity Promoter Regions transcription factors / metabolism transfection transcription factors / genetics viral / genetics genetic / genetics* pmid:8548797 doi:10.1016/0092-8674(95)90136-1 d thanos t maniatis binding sites / physiology hela cells / physiology high mobility group proteins / genetics interferon-beta / genetics* genetic / genetics y chromosome / genetics

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