Therapeutic drug monitoring of amikacin in septic patients

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ID: 267481
2013
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Abstract
TDM resulted in adjustment of AMK therapy in most of our septic patients. Early achievement of an optimal Cpeak/MIC ratio may have an impact on clinical and microbiological responses, but not on outcome. In patients with impaired renal function prior to treatment, AMK therapy may be associated with …
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Authors Duszynska W;Taccone FS;Hurkacz M;Kowalska-Krochmal B;Wiela-Hojeńska A;Kübler A;;
Journal critical care (london, england)
Year 2013
DOI
DOI not found
URL
https://www.ncbi.nlm.nih.gov/pubmed/23886243
Keywords
National Center for Biotechnology Information NCBI NLM MEDLINE humans pubmed abstract nih national institutes of health national library of medicine adult female male aged middle aged sepsis / drug therapy* dose-response relationship drug anti-bacterial agents / therapeutic use* amikacin / therapeutic use* anti-bacterial agents / blood pmid:23886243 pmc4057344 doi:10.1186/cc12844 wieslawa duszynska fabio silvio taccone andrzej kübler amikacin / blood critical illness / therapy* drug monitoring / methods* metabolic clearance rate / physiology sepsis / blood sepsis / diagnosis

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