Low-density lipoprotein receptor-related protein 5 (LRP5) mediates the prostate cancer-induced formation of new bone

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ID: 267345
2008
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Abstract
The tendency of prostate cancer to produce osteoblastic bone metastases suggests that cancer cells and osteoblasts interact in ways that contribute to cancer progression. To identify factors that mediate these interactions, we compared gene expression patterns between two bone-derived prostate cance …
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Authors Li ZG;Yang J;Vazquez ES;Rose D;Vakar-Lopez F;Mathew P;Lopez A;Logothetis CJ;Lin SH;Navone NM;;
Journal Oncogene
Year 2008
DOI
DOI not found
URL
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=17700537
Keywords
Tumor National Center for Biotechnology Information NCBI NLM MEDLINE Mice animals humans pubmed abstract nih national institutes of health national library of medicine research support non-u.s. gov't u.s. gov't non-p.h.s. male N.I.H. Extramural cell line phenotype signal transduction wnt proteins / metabolism* bone neoplasms / metabolism bone neoplasms / secondary* pmid:17700537 doi:10.1038/sj.onc.1210694 z g li j yang n m navone intercellular signaling peptides and proteins / metabolism ldl-receptor related proteins / metabolism* low density lipoprotein receptor-related protein-5 osteoblasts / metabolism osteolysis prostatic neoplasms / metabolism* prostatic neoplasms / pathology

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