Low sulfide levels and a high degree of cystathionine β-synthase (CBS) activation by S-adenosylmethionine (SAM) in the long-lived naked mole-rat

Clicks: 244
ID: 267319
2016
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Abstract
Hydrogen sulfide (H2S) is a gaseous signalling molecule involved in many physiological and pathological processes. There is increasing evidence that H2S is implicated in aging and lifespan control in the diet-induced longevity models. However, blood sulfide concentration of naturally long-lived spec …
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Authors Dziegelewska M;Holtze S;Vole C;Wachter U;Menzel U;Morhart M;Groth M;Szafranski K;Sahm A;Sponholz C;Dammann P;Huse K;Hildebrandt T;Platzer M;;
Journal Redox biology
Year 2016
DOI
DOI not found
URL
https://www.pubmed.gov/?cmd=Search&term=Christopher%20Morhart
Keywords
diet National Center for Biotechnology Information NCBI NLM MEDLINE animals pubmed abstract nih national institutes of health national library of medicine research support non-u.s. gov't Rats liver / enzymology aging / pathology pmid:26803480 pmc4732021 doi:10.1016/j.redox.2016.01.008 maja dziegelewska susanne holtze matthias platzer aging / blood* cystathionine beta-synthase / genetics cystathionine beta-synthase / metabolism* hydrogen sulfide / blood* longevity / genetics methionine / metabolism mole rats s-adenosylmethionine / metabolism*

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