Dickkopf-1 (DKK-1) stimulated prostate cancer growth and metastasis and inhibited bone formation in osteoblastic bone metastases

Clicks: 320
ID: 267314
2011
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Abstract
The present study showed that DKK-1 is a potent inhibitor of bone growth in prostate cancer-induced osteoblastic metastases.
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Authors Thudi NK;Martin CK;Murahari S;Shu ST;Lanigan LG;Werbeck JL;Keller ET;McCauley LK;Pinzone JJ;Rosol TJ;;
Journal the prostate
Year 2011
DOI
DOI not found
URL
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Abstract&list_uids=20957670
Keywords
Tumor National Center for Biotechnology Information NCBI NLM MEDLINE Mice animals pubmed abstract nih national institutes of health national library of medicine research support non-u.s. gov't male N.I.H. Extramural Tomography cell line x-ray computed statistics nonparametric nude dogs signal transduction histocytochemistry Intercellular Signaling Peptides and Proteins / genetics Intercellular Signaling Peptides and Proteins / metabolism* wnt proteins / metabolism* pmid:20957670 pmc3025080 doi:10.1002/pros.21277 nanda k thudi chelsea k martin thomas j rosol bone neoplasms / metabolism bone neoplasms / secondary* cell growth processes / physiology osteogenesis / physiology prostatic neoplasms / metabolism prostatic neoplasms / pathology* wnt proteins / antagonists & inhibitors

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