Neuroinvasive West Nile Infection with an Unusual Clinical Presentation: A Single-Center Case Series

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ID: 267297
2020
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Abstract
The 2018 West Nile Virus (WNV) season in Europe was characterized by an extremely high infection rate and an exceptionally higher burden when compared to previous seasons. Overall, there was a 10.9-fold increase in incidence in Italy, with 577 human cases, 230 WNV neuroinvasive diseases (WNNV) and 42 WNV-attributed deaths. Methods: in this paper we retrospectively reported the neurological presentation of 7 patients admitted to University Hospital of Udine with a diagnosis of WNNV, especially focusing on two patients who presented with atypical severe brain stem involvement. Conclusions: the atypical features of some of these forms highlight the necessity to stay vigilant and suspect the diagnosis when confronted with neurological symptoms. We strongly encourage clinicians to consider WNNV in patients presenting with unexplained neurological symptoms in mild climate-areas at risk.
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castaldo2020tropicalneuroinvasive Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors Nadia Castaldo;Elena Graziano;Maddalena Peghin;Tolinda Gallo;Pierlanfranco D’Agaro;Assunta Sartor;Tiziana Bove;Roberto Cocconi;Giovanni Merlino;Matteo Bassetti;Castaldo, Nadia;Graziano, Elena;Peghin, Maddalena;Gallo, Tolinda;D’Agaro, Pierlanfranco;Sartor, Assunta;Bove, Tiziana;Cocconi, Roberto;Merlino, Giovanni;Bassetti, Matteo;
Journal Tropical medicine and infectious disease
Year 2020
DOI
10.3390/tropicalmed5030138
URL
https://www.mdpi.com/2414-6366/5/3/138/htm
Keywords
flavivirus vector west nile virus mosquitos artropodes neuroinvasiveness

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