Association of the APC gene product with beta-catenin

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ID: 267097
1993
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Abstract
Mutations in the human APC gene are linked to familial adenomatous polyposis and to the progression of sporadic colorectal and gastric tumors. To gain insight into APC function, APC-associated proteins were identified by immunoprecipitation experiments. Antibodies to APC precipitated a 95-kilodalton …
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Authors Rubinfeld B;Souza B;Albert I;Müller O;Chamberlain SH;Masiarz FR;Munemitsu S;Polakis P;;
Journal Science (New York, N.Y.)
Year 1993
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