The mechanism and regulation of deadenylation: identification and characterization of Xenopus PARN

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ID: 266979
2001
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Abstract
In Xenopus oocytes, the deadenylation of a specific class of maternal mRNAs results in their translational repression. Here we report the purification, characterization, and molecular cloning of the Xenopus poly(A) ribonuclease (xPARN). xPARN copurifies with two polypeptides of 62 kDa and 74 kDa, an …
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Authors Copeland PR;Wormington M;;
Journal RNA (New York, N.Y.)
Year 2001
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