A glutamine-rich hydrophobic patch in transcription factor Sp1 contacts the dTAFII110 component of the Drosophila TFIID complex and mediates transcriptional activation

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ID: 266920
1994
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Ranked #30 of 292 articles by views in Proceedings of the National Academy of Sciences of the United States of America

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Abstract
Activation of transcription by the promoter-specific factor Sp1 requires coactivators that are tightly associated with the TATA-box-binding protein (TBP) in the TFIID complex. Recent work has shown that the two glutamine-rich activation domains of Sp1, A and B, can interact with at least one compone …
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g1994proceedingsa Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors Gill G;Pascal E;Tseng ZH;Tjian R;;
Journal Proceedings of the National Academy of Sciences of the United States of America
Year 1994
DOI
DOI not found
URL
http://www.ncbi.nlm.nih.gov/pubmed/8278363
Keywords
National Center for Biotechnology Information NCBI NLM MEDLINE animals pubmed abstract nih national institutes of health national library of medicine research support non-u.s. gov't amino acid sequence sequence alignment Comparative Study Cells Cultured genetic* Transcription Factors / metabolism* Molecular Sequence Data in vitro techniques transcription sequence homology amino acid solubility transcriptional activation structure-activity relationship macromolecular substances sp1 transcription factor / metabolism* dna mutational analysis pmid:8278363 pmc42912 doi:10.1073/pnas.91.1.192 g gill e pascal r tjian drosophila melanogaster glutamine / chemistry sp1 transcription factor / chemistry transcription factor tfiid

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