Altered circulating leukocytes and their chemokines in a clinical trial of therapeutic hypothermia for neonatal hypoxic ischemic encephalopathy*

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ID: 266667
2013
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Abstract
Our data are consistent with chemokine-associated systemic immunosuppression with hypothermia treatment. In hypothermic neonates, persistence of lower leukocyte counts after rewarming is observed in infants with more severe CNS injury.
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Authors Jenkins DD;Lee T;Chiuzan C;Perkel JK;Rollins LG;Wagner CL;Katikaneni LP;Bass WT;Kaufman DA;Horgan MJ;Laungani S;Givelichian LM;Sankaran K;Yager JY;Martin R;;
Journal Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies
Year 2013
DOI
DOI not found
URL
http://www.ncbi.nlm.nih.gov/pubmed/23897243
Keywords
National Center for Biotechnology Information NCBI NLM MEDLINE humans pubmed abstract nih national institutes of health national library of medicine treatment outcome research support non-u.s. gov't female male N.I.H. Extramural Infant newborn Randomized Controlled Trial Multicenter Study time factors intensive care units leukocyte count hypoxia-ischemia hypothermia neonatal pmid:23897243 doi:10.1097/pcc.0b013e3182975cc9 dorothea d jenkins timothy lee renee martin chemokines / blood* induced* brain / blood* brain / therapy* leukocytes / physiology*

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