MicroRNA-181c Inhibits Interleukin-6-mediated Beta Cell Apoptosis by Targeting TNF-α Expression

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ID: 266662
2019
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Abstract
We have previously reported that long-term treatment of beta cells with interleukin-6 (IL-6) is pro-apoptotic. However, little is known about the regulatory mechanisms that are involved. Therefore, we investigated pro-apoptotic changes in mRNA expression in beta cells in response to IL-6 treatment. …
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Authors Oh YS;Bae GD;Park EY;Jun HS;;
Journal molecules
Year 2019
DOI
DOI not found
URL
https://www.pubmed.gov/30974824/
Keywords
Tumor National Center for Biotechnology Information NCBI NLM MEDLINE Mice animals pubmed abstract nih national institutes of health national library of medicine yoon sin oh hee-sook jun Rats cell line Gene Expression Regulation* micrornas / metabolism* apoptosis insulin-secreting cells / metabolism* pmid:30974824 pmc6480349 doi:10.3390/molecules24071410 gong deuk bae insulin-secreting cells / cytology interleukin-6 / metabolism* tumor necrosis factor-alpha / biosynthesis*

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