Human natural killer cells exhibit direct activity against Aspergillus fumigatus hyphae, but not against resting conidia

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ID: 266625
2011
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Abstract
Because natural killer (NK) cells kill tumor cells and combat infections, there is growing interest in adoptively transferring NK cells to hematopoietic stem cell recipients. Unfortunately, in humans, the activity of NK cells against Aspergillus species, the major cause of invasive fungal infection …
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Authors Schmidt S;Tramsen L;Hanisch M;Latgé JP;Huenecke S;Koehl U;Lehrnbecher T;;
Journal The Journal of infectious diseases
Year 2011
DOI
DOI not found
URL
https://www.ncbi.nlm.nih.gov/pubmed/21208932
Keywords
National Center for Biotechnology Information NCBI NLM MEDLINE gene expression regulation humans pubmed abstract nih national institutes of health national library of medicine research support non-u.s. gov't Cells Cultured interferon-gamma / genetics spores chemokine ccl5 / metabolism killer cells interferon-gamma / metabolism pmid:21208932 pmc3071101 doi:10.1093/infdis/jiq062 stanislaw schmidt lars tramsen thomas lehrnbecher aspergillus fumigatus / immunology aspergillus fumigatus / physiology* chemokine ccl5 / genetics granulocyte-macrophage colony-stimulating factor / genetics granulocyte-macrophage colony-stimulating factor / metabolism hyphae / immunology hyphae / physiology* interleukin-2 / genetics interleukin-2 / metabolism natural / physiology* fungal / immunology fungal / physiology*

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