Agouti regulates adipocyte transcription factors

Clicks: 334
ID: 266538
2001
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Abstract
Agouti is a secreted paracrine factor that regulates pigmentation in hair follicle melanocytes. Several dominant mutations cause ectopic expression of agouti, resulting in a phenotype characterized by yellow fur, adult-onset obesity and diabetes, increased linear growth and skeletal mass, and increa …
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Authors Mynatt RL;Stephens JM;;
Journal American journal of physiology. Cell physiology
Year 2001
DOI
DOI not found
URL
http://www.ncbi.nlm.nih.gov/pubmed/11245612
Keywords
National Center for Biotechnology Information NCBI NLM MEDLINE Mice RNA animals pubmed abstract nih national institutes of health national library of medicine research support non-u.s. gov't u.s. gov't male P.H.S. Adipocytes / physiology* phenotype Body Weight 3T3 Cells Receptors Leptin / genetics transcription cytoplasmic and nuclear / metabolism transcription factors / metabolism signal transduction / physiology proteins / genetics* transgenic stat3 transcription factor messenger / analysis dna-binding proteins / metabolism gene expression / physiology trans-activators / metabolism pmid:11245612 doi:10.1152/ajpcell.2001.280.4.c954 r l mynatt j m stephens agouti signaling protein intercellular signaling peptides and proteins* proteins / metabolism* stat1 transcription factor genetic / physiology* alpha-msh / metabolism

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