Transcriptional down-regulation of metabolic genes by Gdown1 ablation induces quiescent cell re-entry into the cell cycle
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ID: 266532
2020
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Abstract
Liver regeneration and metabolism are highly interconnected. Here, we show that hepatocyte-specific ablation of RNA polymerase II (Pol II)-associated Gdown1 leads to down-regulation of highly expressed genes involved in plasma protein synthesis and metabolism, ...
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| Reference Key |
roeder2020genestranscriptional
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|---|---|
| Authors | Miki Jishage, Keiichi Ito, Chi-Shuen Chu, Xiaoling Wang, Masashi Yamaji, Robert G. Roeder;Miki Jishage;Keiichi Ito;Chi-Shuen Chu;Xiaoling Wang;Masashi Yamaji;Robert G. Roeder; |
| Journal | genes & development |
| Year | 2020 |
| DOI |
10.1101/gad.337683.120
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| URL | |
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