Nucleosome disruption and enhancement of activator binding by a human SW1/SNF complex

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1994
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Abstract
CHROMATIN structure can affect the transcriptional activity of eukaryotic structural genes by blocking access of sequence-specific activator proteins (activators) to their promoter-binding sites. For example, the DNA-binding domain of the yeast GAL4 protein interacts very poorly with nucleosome core …
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Journal Nature
Year 1994
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