Mutations, mutation rates, and evolution at the hypervariable VNTR loci of Yersinia pestis

Clicks: 284
ID: 266478
2007
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Abstract
VNTRs are able to discriminate among closely related isolates of recently emerged clonal pathogens, including Yersinia pestis the etiologic agent of plague, because of their great diversity. Diversity is driven largely by mutation but little is known about VNTR mutation rates, factors affecting muta …
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Authors Vogler AJ;Keys CE;Allender C;Bailey I;Girard J;Pearson T;Smith KL;Wagner DM;Keim P;;
Journal mutation research
Year 2007
DOI
DOI not found
URL
http://www.ncbi.nlm.nih.gov/pubmed/17161849
Keywords
Evolution databases National Center for Biotechnology Information NCBI NLM MEDLINE genetic animals pubmed abstract nih national institutes of health national library of medicine research support non-u.s. gov't u.s. gov't non-p.h.s. N.I.H. Extramural DNA Molecular* Phylogeny Genotype disease outbreaks gene dosage dogs plague / epidemiology mutation* plague / transmission bacterial / genetics* yersinia pestis / genetics* pmid:17161849 doi:10.1016/j.mrfmmm.2006.11.007 amy j vogler christine e keys paul keim genetic variation* minisatellite repeats*

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