Hepatitis C Virus-Infected Patients Receiving Opioid Substitution Therapy Experience Improvement in Patient-Reported Outcomes Following Treatment With Interferon-Free Regimens

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ID: 266289
2018
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Abstract
Receiving IFN-free regimens leads to PRO improvement during treatment and after the SVR-12, regardless of OST status. HCV-infected subjects receiving OST did not experience similar PRO improvements with IFN-containing therapy, suggesting that IFN-based therapy may be less suitable for this vulnerabl …
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Authors Stepanova M;Thompson A;Doyle J;Younossi I;de Avila L;Younossi ZM;;
Journal The Journal of infectious diseases
Year 2018
DOI
DOI not found
URL
http://www.ncbi.nlm.nih.gov/pubmed/29293991
Keywords
hepatitis c National Center for Biotechnology Information NCBI NLM MEDLINE humans pubmed abstract nih national institutes of health national library of medicine treatment outcome research support non-u.s. gov't adult female male middle aged drug therapy combination antiviral agents / therapeutic use* ribavirin / administration & dosage ribavirin / therapeutic use chronic / drug therapy* hepacivirus sofosbuvir / therapeutic use pmid:29293991 doi:10.1093/infdis/jix681 maria stepanova alexander thompson zobair m younossi interferons / administration & dosage* interferons / therapeutic use opiate substitution treatment* patient reported outcome measures* sofosbuvir / administration & dosage sustained virologic response

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