SREBP-1, a basic-helix-loop-helix-leucine zipper protein that controls transcription of the low density lipoprotein receptor gene

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ID: 266238
1993
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Abstract
Sterol regulatory element 1 (SRE-1), a decamer (5'-ATC-ACCCCAC-3') flanking the low density lipoprotein (LDL) receptor gene, activates transcription in sterol-depleted cells and is silenced by sterols. We report the cDNA cloning of human SREBP-1, a protein that binds SRE-1, activates transcription, …
Reference Key
c1993cellsrebp-1, Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors Yokoyama C, Wang X, Briggs MR, Admon A, Wu J, Hua X, Goldstein JL, Brown MS
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Journal Cell
Year 1993
DOI
DOI not found
URL
http://www.ncbi.nlm.nih.gov/pubmed/8402897
Keywords
National Center for Biotechnology Information NCBI NLM MEDLINE genetic Molecular RNA humans pubmed abstract nih national institutes of health national library of medicine research support non-u.s. gov't u.s. gov't amino acid sequence Comparative Study P.H.S. DNA x wang DNA-Binding Proteins / metabolism* Nuclear Proteins / metabolism* Receptors Base Sequence Molecular Sequence Data DNA-Binding Proteins / biosynthesis Gene Expression Regulation* Nuclear Proteins / biosynthesis Messenger / biosynthesis transcription messenger / metabolism sequence homology amino acid nucleic acid dna primers cloning recombinant proteins / biosynthesis regulatory sequences repetitive sequences hela cells dna-binding proteins / isolation & purification nuclear proteins / isolation & purification binding sites cell nucleus / metabolism transcription factors* sterol regulatory element binding protein 1 leucine zippers* recombinant proteins / metabolism ldl / genetics* pmid:8402897 c yokoyama m s brown ccaat-enhancer-binding proteins* complementary / metabolism helix-loop-helix motifs* ldl / biosynthesis* nucleic acid*

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