Chromatin, TAFs, and a novel multiprotein coactivator are required for synergistic activation by Sp1 and SREBP-1a in vitro

Clicks: 285
ID: 265940
1998
Free PDF
Article Quality & Performance Metrics
Overall Quality
Not rated
Combines reader engagement with the AI quality analysis. This article has not been analysed, so there is no overall score — reader engagement is measured and shown alongside.
AI Quality Assessment
Not analyzed
Readership in this journal
Popular

Ranked #26 of 206 articles by views in genes & development

Most read Least read

Bar heights use a square-root scale. Only the 120 most-read articles are drawn; the journal has 206 in total.

Mint this article as an NFT
Not yet minted

Create a permanent, verifiable on-chain record of this article on the Scimatic Network. The NFT is held in your Journament account, and you can withdraw it to your own wallet at any time.

5 SUSD one-off · no wallet required
Sign in to mint
Abstract
The promoter selectivity factor Sp1 often cooperates with other enhancer-binding proteins to activate transcription. To study the molecular underpinnings of these regulatory events, we have reconstituted in vitro the synergy observed in vivo between Sp1 ...
Reference Key
tjian1998geneschromatin, Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors Anders M. Näär, Pierre A. Beaurang, Karen M. Robinson, Jon D. Oliner, Daina Avizonis, Sigrid Scheek, Jörk Zwicker, James T. Kadonaga, Robert Tjian;Anders M. Näär;Pierre A. Beaurang;Karen M. Robinson;Jon D. Oliner;Daina Avizonis;Sigrid Scheek;Jörk Zwicker;James T. Kadonaga;Robert Tjian;
Journal genes & development
Year 1998
DOI
10.1101/gad.12.19.3020
URL
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC317191/
Keywords
National Center for Biotechnology Information NCBI NLM MEDLINE genetic Drosophila animals humans pubmed abstract nih national institutes of health national library of medicine models research support non-u.s. gov't u.s. gov't P.H.S. Receptors DNA-Binding Proteins / physiology* Nuclear Proteins / physiology* Promoter Regions hela cells drug synergism transcription factors* sterol regulatory element binding protein 1 chromatin / physiology* ccaat-enhancer-binding proteins* LDL / genetics r tjian transcription factor tfiid transcriptional activation* pmid:9765204 pmc317191 doi:10.1101/gad.12.19.3020 a m näär p a beaurang helix-loop-helix motifs / physiology* leucine zippers / physiology* sp1 transcription factor / physiology* transcription factors tfii / physiology

Citations

No citations found. To add a citation, contact the admin at info@scimatic.org

Comments

No comments yet. Be the first to comment on this article.