Relationship between the effect of cyclophosphamide on adjuvant arthritis severity, skin allograft rejection and spleen cell cytotoxic activity in rats

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ID: 265903
1990
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Abstract
Cyclophosphamide, which has a poor immunosuppressive effect on adjuvant arthritis in rats, evokes an aggravating form of the disease when applied at a single low dose before rats' sensitization with complete Freund's adjuvant. However, cyclophosphamide administered by this method of treatment has no …
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Authors Marinova-Mutafchieva L;Altankov G;Neronov A;Goranov I;;
Journal Methods and findings in experimental and clinical pharmacology
Year 1990
DOI
DOI not found
URL
https://www.ncbi.nlm.nih.gov/pubmed/2319832
Keywords
immunity National Center for Biotechnology Information NCBI NLM MEDLINE animals pubmed abstract nih national institutes of health national library of medicine Rats spleen / drug effects arthritis experimental / drug therapy* inbred strains pmid:2319832 l marinova-mutafchieva g altankov i goranov arthritis / drug therapy* cell survival / drug effects* chromium radioisotopes cyclophosphamide / pharmacology* graft rejection / drug effects* cellular / drug effects skin transplantation spleen / cytology spleen / immunology*

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