Chronic testosterone treatment induces selective insulin resistance in subcutaneous adipocytes of women

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ID: 265685
2007
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Abstract
Adipose tissue plays a central role in determining whole body insulin sensitivity. Several aspects of adipose cell function are regulated by androgens. Given that high androgen levels and insulin resistance are linked in women, we proposed that androgens may influence insulin-mediated glucose metabo …
Reference Key
a2007thechronic Use this key to autocite in the manuscript while using SciMatic Manuscript Manager or Thesis Manager
Authors Corbould A;;
Journal the journal of endocrinology
Year 2007
DOI
DOI not found
URL
http://www.ncbi.nlm.nih.gov/pubmed/17332526
Keywords
National Center for Biotechnology Information NCBI NLM MEDLINE humans pubmed abstract nih national institutes of health national library of medicine research support non-u.s. gov't adult female Cells Cultured Proto-Oncogene Proteins c-akt / metabolism Insulin Resistance* Biological Transport / drug effects Cell Differentiation / drug effects flutamide / pharmacology glucose / metabolism adipocytes / metabolism* testosterone / pharmacology* analysis of variance polycystic ovary syndrome / metabolism hypoglycemic agents / pharmacology signal transduction reverse transcriptase polymerase chain reaction insulin / metabolism phosphorylation insulin / pharmacology insulin receptor substrate proteins pmid:17332526 doi:10.1677/joe.1.07070 a corbould cyproterone acetate / pharmacology phosphoproteins / metabolism protein kinase c / metabolism subcutaneous fat / metabolism*

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