Synthetic and Therapeutic Interest of Amidines
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ID: 265436
2020
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Abstract
Amidines, structural units of a large number of biologically active molecules (antiparasitic,
antidiabetic, anti-cancer, anti-inflammatory, anti-malarial,...), many compounds of biological interest,
bioactive natural products and certain drugs, constitute synthons useful in organic synthesis. They are
important intermediates for the synthesis of many nitrogenous heterocyclic compounds (pyridines,
pyrimidines, benzimidazoles, ... and 1,2,4-triazoles). The multiple methods for obtaining amidines from
various nitrogen compounds, and their use in organic synthesis and in therapeutics are described in this
bibliographic review.
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adiche2020syntheticphytochem
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| Authors | Adiche, Chiaa;, Douniazad El Abed; |
| Journal | phytochemistry & bioactives substances journal |
| Year | 2020 |
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